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Two distinct lineages of chikungunya virus cocirculated in Aruba during the 2014-2015 epidemic

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dc.contributor.author Phadungsombat, J. en_US
dc.contributor.author Tuekprakhon, A. en_US
dc.contributor.author Cnops, L. en_US
dc.contributor.author Michiels, J. en_US
dc.contributor.author Van Den Berg, R. en_US
dc.contributor.author Nakayama, E. E. en_US
dc.contributor.author Shioda, T. en_US
dc.contributor.author Ariën, K. K. en_US
dc.contributor.author Huits, R. en_US
dc.date.accessioned 2020-08-25T09:38:07Z
dc.date.available 2020-08-25T09:38:07Z
dc.date.issued 2020 en_US
dc.identifier.issn 1567-1348 en_US
dc.identifier.doi http://dx.doi.org/10.1016/j.meegid.2019.104129 en_US
dc.identifier.other ITG-C3A; ITG-B4A; ITG-B8A; ITG-CLA; MULTI; DCS; U-HIVNTD; U-TRAVM; DBM; U-VIROL; JIF; DOI; CPDF; Abstract; ITMPUB; DSPACE68 en_US
dc.identifier.uri http://hdl.handle.net/10390/10881
dc.description.abstract Chikungunya virus (CHIKV), a positive-sense, single-stranded RNA virus in the family Togaviridae, is transmitted by Aedes mosquitoes. Of three known CHIKV genotypes, the Asian genotype was introduced into the Caribbean islands and rapidly spread throughout Central and South Americas. We previously found patients with symptoms compatible with chikungunya fever in 2014-2015 in Aruba, a Caribbean island of 180km(2). We here describe the full genome sequences of eight CHIKV strains isolated from patient sera of the Aruban outbreak. Phylogenetic analysis revealed that two closely related but distinct lineages of Asian-genotype CHIKV circulated simultaneously during the epidemic in 2014-2015. These results suggested that CHIKV was introduced into Aruba more than once in a short period, reflecting the importance of Aruba as a travel hub within the region. en_US
dc.language English en_US
dc.relation.uri http://www.ncbi.nlm.nih.gov/pubmed/31786339 en_US
dc.subject Chikungunya virus disease en_US
dc.subject Viral diseases en_US
dc.subject Outbreaks en_US
dc.subject Aruba en_US
dc.subject West Indies en_US
dc.subject America-Latin en_US
dc.title Two distinct lineages of chikungunya virus cocirculated in Aruba during the 2014-2015 epidemic en_US
dc.type Article en_US
dc.citation.jtitle Infection, Genetics and Evolution en_US
dc.citation.volume 78 en_US
dc.citation.pages 104129 en_US
dc.citation.abbreviation Infect Genet Evol en_US


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