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Clinical evaluation of QuickNavi(TM)-Ebola in the 2018 outbreak of Ebola virus disease in the Democratic Republic of the Congo

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dc.contributor.author Makiala, S. en_US
dc.contributor.author Mukadi, D. en_US
dc.contributor.author De Weggheleire, A. en_US
dc.contributor.author Muramatsu, S. en_US
dc.contributor.author Kato, D. en_US
dc.contributor.author Inano, K. en_US
dc.contributor.author Gondaira, F. en_US
dc.contributor.author Kajihara, M. en_US
dc.contributor.author Yoshida, R. en_US
dc.contributor.author Changula, K. en_US
dc.contributor.author Mweene, A. en_US
dc.contributor.author Mbala-Kingebeni, P. en_US
dc.contributor.author Muyembe-Tamfum, J. J. en_US
dc.contributor.author Masumu, J. en_US
dc.contributor.author Ahuka, S. en_US
dc.contributor.author Takada, A. en_US
dc.date.accessioned 2020-08-25T09:55:02Z
dc.date.available 2020-08-25T09:55:02Z
dc.date.issued 2019 en_US
dc.identifier.issn 1999-4915 en_US
dc.identifier.doi http://dx.doi.org/10.3390/v11070589 en_US
dc.identifier.other http://lib.itg.be/pdf/itg/2019/2019viru0001.pdf en_US
dc.identifier.other 7 pp. en_US
dc.identifier.other 14 en_US
dc.identifier.other ITG-C3A; DCS; U-HIVNTD; JIF; DOI; PDF; Abstract; ITMPUB; DSPACE68 en_US
dc.identifier.uri http://hdl.handle.net/10390/11102
dc.description.abstract The recent large outbreaks of Ebola virus disease (EVD) in West Africa and the Democratic Republic of the Congo (DRC) have highlighted the need for rapid diagnostic tests to control this disease. In this study, we clinically evaluated a previously developed immunochromatography-based kit, QuickNavi(TM)-Ebola. During the 2018 outbreaks in DRC, 928 blood samples from EVD-suspected cases were tested with QuickNavi(TM)-Ebola and the WHO-approved GeneXpert. The sensitivity and specificity of QuickNavi(TM)-Ebola, estimated by comparing it to GeneXpert-confirmed cases, were 85% (68/80) and 99.8% (846/848), respectively. These results indicate the practical reliability of QuickNavi(TM)-Ebola for point-of-care diagnosis of EVD. en_US
dc.language English en_US
dc.relation.uri http://www.ncbi.nlm.nih.gov/pubmed/31261668 en_US
dc.subject Ebola virus disease en_US
dc.subject Viral diseases en_US
dc.subject Outbreaks en_US
dc.subject Rapid diagnostic tests en_US
dc.subject QuickNavi Ebola en_US
dc.subject Evaluation en_US
dc.subject Congo-Kinshasa en_US
dc.subject Africa-Central en_US
dc.title Clinical evaluation of QuickNavi(TM)-Ebola in the 2018 outbreak of Ebola virus disease in the Democratic Republic of the Congo en_US
dc.type Article-E en_US
dc.citation.issue 7 en_US
dc.citation.jtitle Viruses en_US
dc.citation.volume 11 en_US
dc.citation.abbreviation Viruses en_US


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