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Identification of a new variable number tandem repeat locus in Mycobacterium ulcerans for potential strains discrimination among African isolates

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dc.contributor.author Ablordey, A. en_US
dc.contributor.author Fonteyne, P. A. en_US
dc.contributor.author Stragier, P. en_US
dc.contributor.author Vandamme, P. en_US
dc.contributor.author Portaels, F. en_US
dc.date.accessioned 2007-12-06T14:46:18Z
dc.date.available 2007-12-06T14:46:18Z
dc.date.issued 2007 en_US
dc.identifier.issn 1198-743X en_US
dc.identifier.doi http://dx.doi.org/10.1111/j.1469-0691.2007.01716.x
dc.identifier.other ITG-M1B en_US
dc.identifier.other ITG-M3B en_US
dc.identifier.other ITG-MLA en_US
dc.identifier.other MICRO en_US
dc.identifier.other U-MYCOB en_US
dc.identifier.other JIF en_US
dc.identifier.other DOI en_US
dc.identifier.other ABSTRACT en_US
dc.identifier.uri http://hdl.handle.net/10390/1646
dc.description The definitive version is available at www3.interscience.wiley.com en_US
dc.description.abstract Intra-species discrimination in the highly clonal pathogen Mycobacterium ulcerans was studied in a diverse collection of isolates by PCR amplification of a short sequence repeat locus containing heterogeneous arrays of tri-nucleotide repeats with an ACC consensus pattern. Post-amplification analysis indicated excellent typeability and identified five M. ulcerans alleles, including a unique Angolan type differentiated for the first time among a genetically conserved cluster of African isolates. These results are consistent with previously investigated independent markers, and provide an additional locus for variable number tandem repeat-based typing of M. ulcerans. en_US
dc.language English en_US
dc.publisher Blackwell Publishing en_US
dc.subject Bacteriology en_US
dc.subject Mycobacterium ulcerans en_US
dc.subject Strains en_US
dc.subject Species en_US
dc.subject Identification en_US
dc.subject Molecular diagnostic techniques en_US
dc.subject PCR en_US
dc.subject Laboratory techniques and procedures en_US
dc.title Identification of a new variable number tandem repeat locus in Mycobacterium ulcerans for potential strains discrimination among African isolates en_US
dc.type Article en_US
dc.citation.issue 7 en_US
dc.citation.jtitle Clinical Microbiology and Infection en_US
dc.citation.volume 13 en_US
dc.citation.pages 734-736 en_US
dc.publisher.place Oxford en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/17403131
dc.citation.jabbreviation Clin Microbiol Infect en_US


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