Institute of Tropical Medicine Antwerp
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Cord C-peptide and insulin-like growth factor-I, birth weight, and placenta weight among North African and Belgian neonates

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dc.contributor.author Delvaux, T. en_US
dc.contributor.author Buekens, P. en_US
dc.contributor.author Thoumsin, H. en_US
dc.contributor.author Dramaix, M. en_US
dc.contributor.author Collette, J. en_US
dc.date.accessioned 2007-12-06T14:46:50Z
dc.date.available 2007-12-06T14:46:50Z
dc.date.issued 2003 en_US
dc.identifier.issn 0002-9378 en_US
dc.identifier.other ITG-M1A en_US
dc.identifier.other MICRO en_US
dc.identifier.other U-HIVSTD en_US
dc.identifier.other JIF en_US
dc.identifier.other ABSTRACT en_US
dc.identifier.uri http://hdl.handle.net/10390/1737
dc.description.abstract OBJECTIVE: Despite their low socioeconomic status, infants of North African immigrants have been reported to have high birth weights in Belgium. The aim of the study was to further explore potential mechanisms explaining this high birth weight. STUDY DESIGN: Venous umbilical cord blood samples and perinatal characteristics of live-born infants from mothers of North African and Belgian nationality were collected in 1997 through 1998 at the University Hospital La Citadelle, Liège, Belgium. RESULTS: The median connecting peptide (C-peptide) concentration was significantly higher among North African than Belgian neonates (0.125 vs 0.110 pmol/mL, P=.04). However, the median insulin-like growth factor-I concentrations among North African and Belgian newborn infants were, respectively, 74.0 and 69.6 ng/mL (P=.45). Nationality remained significantly associated with C-peptide after adjusting for age and parity. C-peptide, insulin-like growth factor-I correlated positively with birth weight and remained significant factors for birth weight after adjusting for confounders in multiple regression. CONCLUSION: These results suggest a link between higher C-peptide levels and birth weights among North African neonates in Belgium. en_US
dc.language English en_US
dc.subject Birth weight en_US
dc.subject C-peptide en_US
dc.subject Insulin-like growth factor I en_US
dc.subject Immigrants en_US
dc.subject Belgium en_US
dc.subject Europe, West en_US
dc.title Cord C-peptide and insulin-like growth factor-I, birth weight, and placenta weight among North African and Belgian neonates en_US
dc.type Article en_US
dc.citation.issue 6 en_US
dc.citation.jtitle American Journal of Obstetrics and Gynecology en_US
dc.citation.volume 189 en_US
dc.citation.pages 1779-1784 en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/14710115
dc.citation.jabbreviation Am J Obstet Gynecol en_US


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