Institute of Tropical Medicine Antwerp
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BCG vaccine effectiveness against Buruli ulcer: a case-control study in Benin

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dc.contributor.author Nackers, F. en_US
dc.contributor.author Dramaix, M. en_US
dc.contributor.author Johnson, R. C. en_US
dc.contributor.author Zinsou, C. en_US
dc.contributor.author Robert, A. en_US
dc.contributor.author de Biurrun Bakedano, E. en_US
dc.contributor.author Glynn, J. R. en_US
dc.contributor.author Portaels, F. en_US
dc.contributor.author Tonglet, R. en_US
dc.date.accessioned 2007-12-06T14:47:41Z
dc.date.available 2007-12-06T14:47:41Z
dc.date.issued 2006 en_US
dc.identifier.issn 0002-9637 en_US
dc.identifier.other ITG-M8A en_US
dc.identifier.other MICRO en_US
dc.identifier.other U-MYCOB en_US
dc.identifier.other JIF en_US
dc.identifier.other ABSTRACT en_US
dc.identifier.other URL
dc.identifier.uri http://hdl.handle.net/10390/1877
dc.description.abstract BCG remains the only possible prophylactic intervention against Buruli ulcer (BU). Estimating its public health impact on BU control is an important issue. We conducted a case-control study to investigate the vaccine effectiveness of routine BCG vaccine against BU in southern Benin. From August 2002 to August 2003, BCG vaccination status was obtained for 279 clinically diagnosed BU cases and 988 age- and sex-matched neighborhood controls. BCG coverage, which was estimated by the presence of a scar or a vaccination record, was 64.5% in cases and 67.2% in controls. There was no evidence of a protective effect of routine BCG vaccination against BU in southern Benin (vaccine effectiveness adjusted for socioeconomic status = 12%, 95% confidence interval = -24% to 37%). en_US
dc.language English en_US
dc.subject Bacterial diseases en_US
dc.subject Buruli ulcer en_US
dc.subject Mycobacterium ulcerans en_US
dc.subject Prevention strategies en_US
dc.subject Vaccination en_US
dc.subject BCG en_US
dc.subject Effectiveness en_US
dc.subject Benin en_US
dc.subject Africa, West en_US
dc.title BCG vaccine effectiveness against Buruli ulcer: a case-control study in Benin en_US
dc.type Article en_US
dc.citation.issue 4 en_US
dc.citation.jtitle American Journal of Tropical Medicine and Hygiene en_US
dc.citation.volume 75 en_US
dc.citation.pages 768-774 en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/17038709
dc.identifier.url http://www.ajtmh.org/cgi/reprint/75/4/768.pdf
dc.citation.jabbreviation Am J Trop Med Hyg en_US


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