Institute of Tropical Medicine Antwerp
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A bayesian evaluation of four immunological assays for the diagnosis of clinical cryptosporidiosis in calves

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dc.contributor.author Geurden, T. en_US
dc.contributor.author Claerebout, E. en_US
dc.contributor.author Vercruysse, J. en_US
dc.contributor.author Berkvens, D. en_US
dc.date.accessioned 2008-07-25T11:36:13Z
dc.date.available 2008-07-25T11:36:13Z
dc.date.issued 2008
dc.identifier.issn 1090-0233
dc.identifier.doi http://dx.doi.org/10.1016/j.tvjl.2007.03.010
dc.identifier.other ITG-ALA en_US
dc.identifier.other ANIMAL en_US
dc.identifier.other U-ANIMAL en_US
dc.identifier.other JIF en_US
dc.identifier.other DOI en_US
dc.identifier.other UPD5 en_US
dc.identifier.other ABSTRACT en_US
dc.identifier.uri http://hdl.handle.net/10390/2336
dc.description.abstract A Bayesian approach was used to evaluate four immunological assays for the clinical diagnosis of cryptosporidiosis in calves: an immunofluorescence assay (IFA), two ELISA tests and an immunochromatographic (dipstick) assay. Faecal samples from 287 calves aged less than 6 weeks with clinical signs of gastrointestinal disease were examined for the presence of Cryptosporidium spp. The high prevalence (63%) of Cryptosporidium spp. indicated the relevance of this agent in the aetiology of diarrhoea in calves. All diagnostic assays were found to be relatively specific (IFA: 94.8%; Tetra ELISA: 95.9%; Techlab ELISA: 92.7%; dipstick assay: 91.5%) and sensitive (IFA: 97.4%; Tetra ELISA: 93.6%; Techlab ELISA: 95.4%; dipstick: 87.8%). Despite a lower sensitivity, the dipstick assay provided a practical alternative to laboratory diagnosis of clinical cryptosporidiosis in calves. en_US
dc.language English en_US
dc.subject Animal diseases en_US
dc.subject Calves en_US
dc.subject Protozoal diseases en_US
dc.subject Cryptosporidiosis en_US
dc.subject Laboratory diagnosis en_US
dc.subject Immunochromatography en_US
dc.subject Dipstick en_US
dc.subject Immunofluorescence en_US
dc.subject ELISA en_US
dc.subject Bayes theorem en_US
dc.subject Evaluation en_US
dc.subject Specificity en_US
dc.subject Sensitivity en_US
dc.subject Comparative study en_US
dc.title A bayesian evaluation of four immunological assays for the diagnosis of clinical cryptosporidiosis in calves en_US
dc.type Article en_US
dc.citation.issue 3 en_US
dc.citation.jtitle Veterinary Journal en_US
dc.citation.volume 176 en_US
dc.citation.pages 400-402 en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/18723290
dc.citation.jabbreviation Vet J en_US


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