Institute of Tropical Medicine Antwerp
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Rapid culture-based methods for drug resistance detection in Mycobacterium tuberculosis

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dc.contributor.author Palomino, J. C.
dc.contributor.author Martin, A.
dc.contributor.author Vor Groll, A.
dc.contributor.author Portaels, F.
dc.date.accessioned 2008-10-28T17:20:04Z
dc.date.available 2008-10-28T17:20:04Z
dc.date.issued 2008
dc.identifier.issn 0167-7012
dc.identifier.doi http://dx.doi.org/10.1016/j.mimet.2008.06.015
dc.identifier.other ITG-M1A
dc.identifier.other ITG-M2A
dc.identifier.other ITG-MLA
dc.identifier.other MICRO
dc.identifier.other U-MYCOB
dc.identifier.other JIF
dc.identifier.other NOT AVAILABLE
dc.identifier.other ABSTRACT
dc.identifier.other UPD7
dc.identifier.uri http://hdl.handle.net/10390/2419
dc.description.abstract Tuberculosis still represents a major public health problem, especially in low-resource countries where the burden of the disease is more important. Multidrug-resistant and extensively drug drug-resistant tuberculosis constitute serious problems for the efficient control of the disease stressing the need to investigate resistance to first- and second-line drugs. Conventional methods for detecting drug-resistance in Mycobacterium tuberculosis are slow and cumbersome. The most commonly used proportion method on Löwenstein-Jensen medium or Middlebrook agar requires a minimum of 3-4 weeks to produce results. Several new approaches have been proposed in the last years for the rapid and timely detection of drug-resistance in tuberculosis. This review will address phenotypic culture-based methods for rapid drug susceptibility testing in M. tuberculosis. en_US
dc.language English en_US
dc.subject Bacterial diseases en_US
dc.subject Tuberculosis en_US
dc.subject Mycobacterium tuberculosis en_US
dc.subject Drug resistance en_US
dc.subject Drug sensitivity testing en_US
dc.subject Rapid assessment en_US
dc.title Rapid culture-based methods for drug resistance detection in Mycobacterium tuberculosis en_US
dc.type Article en_US
dc.citation.issue 2 en_US
dc.citation.jtitle Journal of Microbiological Methods en_US
dc.citation.volume 75 en_US
dc.citation.pages 161-166 en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/18627779
dc.citation.jabbreviation J Microbiol Meth en_US


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