Institute of Tropical Medicine Antwerp
Foundation of Public Utility

A Bayesian modelling framework to estimate Campylobacter prevalence and culture methods sensitivity: application to a chicken meat survey in Belgium

DSpace/Manakin Repository

Show simple item record

dc.contributor.author Habib, I.
dc.contributor.author Sampers, I.
dc.contributor.author Uyttendaele, M.
dc.contributor.author De Zutter, L.
dc.contributor.author Berkvens, D.
dc.date.accessioned 2009-02-13T09:04:56Z
dc.date.available 2009-02-13T09:04:56Z
dc.date.issued 2008
dc.identifier.issn 1364-5072
dc.identifier.doi http://dx.doi.org/10.1111/j.1365-2672.2008.03902.x
dc.identifier.other ITG-ALA
dc.identifier.other ANIMAL
dc.identifier.other U-ANIMAL
dc.identifier.other JIF
dc.identifier.other DOI
dc.identifier.other UPD9
dc.identifier.other ABSTRACT
dc.identifier.uri http://hdl.handle.net/10390/2501
dc.description.abstract AIMS: To estimate the true prevalence of Campylobacter and the diagnostic sensitivity of routine detection methods by applying a Bayesian modelling approach. METHODS AND RESULTS: Results from a Belgium-wide survey of Campylobacter contamination in chicken meat preparations (n = 656 samples) showed that Campylobacter was detected in 24.2% of the samples by enrichment, compared with 41% detected by direct plating. Combining positive results from both methods increased the apparent prevalence to 48.02%. Bayesian model was set up in WinBUGS software, the model estimates Campylobacter prevalence as 60% (95% Credibility interval (CI): 47-82%), and the sensitivity of enrichment culture and direct plating as 41% (95% CI: 31-52%) and 69% (95% CI: 50-85%), respectively. CONCLUSIONS: The parallel use of direct plating and enrichment culture adds value for Campylobacter detection from chicken meat preparations, but the false-negative results from each culture method must be taken into account. SIGNIFICANCE AND IMPACT OF THE STUDY: Monitoring data could be strongly biased by the microbiological techniques used to generate it. To circumvent this bias, we describe an applied Bayesian framework for better interpretation of Campylobacter survey data in view of the imperfect test characteristics of routine culture methods. en
dc.language English en
dc.subject Meat inspection en
dc.subject Chicken meat en
dc.subject Campylobacter en
dc.subject Case detection en
dc.subject Laboratory diagnosis en
dc.subject Methods en
dc.subject Sensitivity en
dc.subject Prevalence en
dc.subject Estimation en
dc.subject Bias en
dc.subject Evaluation en
dc.subject Data analysis en
dc.subject Modeling en
dc.subject Bayes theorem en
dc.subject Belgium en
dc.subject Europe, West en
dc.title A Bayesian modelling framework to estimate Campylobacter prevalence and culture methods sensitivity: application to a chicken meat survey in Belgium en
dc.type Article en
dc.citation.issue 6 en
dc.citation.jtitle Journal of Applied Microbiology en
dc.citation.volume 105 en
dc.citation.pages 2002-2008 en
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/19120647
dc.citation.jabbreviation J Appl Microbiol en


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record