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Evaluation of leishmanin skin test in Indian visceral leishmaniasis

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dc.contributor.author Gidwani, K.
dc.contributor.author Rai, M.
dc.contributor.author Chakravarty, J.
dc.contributor.author Boelaert, M.
dc.contributor.author Sundar, S.
dc.date.accessioned 2009-05-18T09:07:49Z
dc.date.available 2009-05-18T09:07:49Z
dc.date.issued 2009
dc.identifier.issn 0002-9637
dc.identifier.other ITG-H4A
dc.identifier.other HEALTH
dc.identifier.other U-EPID
dc.identifier.other JIF
dc.identifier.other UPD13
dc.identifier.other ABSTRACT
dc.identifier.uri http://hdl.handle.net/10390/2636
dc.description.abstract We evaluated the performance of the leishmanin skin test (LST) in 50 patients with visceral leishmaniasis (VL), 124 cured VL patients at different time intervals, 125 healthy controls from an endemic region (HEC), and 14 healthy controls from a non-endemic region (NEHC). The leishmanin antigen used was based on Leishmania major and was obtained from the Pasteur Institute (Iran). A positive LST was found in 14.0% of patients with active VL, 40.3% of cured patients, 21.6% of HECs, and 0% in NEHCs. The 14% positivity in patients with active VL conflicts with the widely held opinion that such patients should be negative because of anergy. Also, a lack of sensitivity of the LST was observed in cured VL patients. An LST antigen produced from L. donovani strains from India should be explored. en
dc.language English en
dc.publisher American Society of Tropical Medicine and Hygiene en
dc.subject Protozoal diseases en
dc.subject Leishmaniasis en
dc.subject Visceral en
dc.subject Diagnosis en
dc.subject Skin tests en
dc.subject Leishmania major en
dc.subject Leishmania donovani en
dc.subject Evaluation en
dc.subject India en
dc.subject Asia, South en
dc.title Evaluation of leishmanin skin test in Indian visceral leishmaniasis en
dc.type Article en
dc.citation.issue 4 en
dc.citation.jtitle American Journal of Tropical Medicine and Hygiene en
dc.citation.volume 80 en
dc.citation.pages 566-567 en
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/19346376
dc.citation.jabbreviation Am J Trop Med Hyg en


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