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Refinement recommendations for intravenous injection and body heat conservation in Mongolian gerbils used in SPECT studies

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dc.contributor.author Moons, C. P. H.
dc.contributor.author Peremans, K.
dc.contributor.author Büscher, P.
dc.contributor.author Vermeire, S.
dc.contributor.author Vandermeulen, E.
dc.contributor.author Audenaert, K.
dc.contributor.author Hermans, K.
dc.contributor.author Odberg, F. O.
dc.date.accessioned 2009-06-11T14:17:48Z
dc.date.available 2009-06-11T14:17:48Z
dc.date.issued 2008
dc.identifier.issn 0901-3393
dc.identifier.other ITG-P3A
dc.identifier.other PARAS
dc.identifier.other U-SEROL
dc.identifier.other JIF
dc.identifier.other UPD14
dc.identifier.other ABSTRACT
dc.identifier.other NOT AVAILABLE
dc.identifier.uri http://hdl.handle.net/10390/2689
dc.description.abstract This paper describes two aspects of Single Photon Emission Computed Tomography (SPECT) which have been refined for use in small animals, as demonstrated by a study on Mongolian gerbils: intravenous injection of radiotracers in the femoral vein and body heat conservation in animals anaesthetized at the time of scanning. Elaborating on recommendations made by other authors, we have combined chemical and physical restraint to optimize injection efficiency as well as to reduce handling time of the animals. Finally, we provide a detailed description of a SPECT compatible water-heated scanning bed, the application of which we believe is not limited to scintigraphic studies. en
dc.language English en
dc.subject Laboratory animals en
dc.subject Gerbils en
dc.subject Injections en
dc.subject Body heat en
dc.subject Recommendations en
dc.title Refinement recommendations for intravenous injection and body heat conservation in Mongolian gerbils used in SPECT studies en
dc.type Article en
dc.citation.issue 4 en
dc.citation.jtitle Scandinavian Journal of Laboratory Animal Science en
dc.citation.volume 35 en
dc.citation.pages 251-257 en
dc.citation.jabbreviation Scand J Lab Anim Sci en


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