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Strongyloidiasis; the most neglected of the neglected tropical diseases?

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dc.contributor.author Olsen, A.
dc.contributor.author van Lieshout, L.
dc.contributor.author Marti, H.
dc.contributor.author Polderman, T.
dc.contributor.author Polman, K.
dc.contributor.author Steinmann, P.
dc.contributor.author Stothard, R.
dc.contributor.author Thybo, S.
dc.contributor.author Verweij, J. J.
dc.contributor.author Magnussen, P.
dc.date.accessioned 2009-12-21T15:43:12Z
dc.date.available 2009-12-21T15:43:12Z
dc.date.issued 2009
dc.identifier.issn 0035-9203
dc.identifier.doi http://dx.doi.dx/10.1016/j.trstmh.2009.02.013
dc.identifier.other ITG-P5A
dc.identifier.other PARAS
dc.identifier.other U-SCHISTO
dc.identifier.other JIF
dc.identifier.other DOI
dc.identifier.other UPD17
dc.identifier.other ABSTRACT
dc.identifier.uri http://hdl.handle.net/10390/2872
dc.description.abstract Soil-transmitted helminths of the genus Strongyloides (S. fuelleborni and the more prevalent S. stercoralis) are currently believed to infect an estimated 30-100 million people worldwide. The health consequences of S. stercoralis infections range from asymptomatic light infections to chronic symptomatic strongyloidiasis. Uncontrolled multiplication of the parasite (hyperinfection) and potentially life-threatening dissemination of larvae to all internal organs is found among individuals with compromised immune system functions. This paper provides an overview of the current state of the art in relation to diagnostic methods for detecting the infection, the morbidity caused by the infection and the recommended treatment. It further discusses some of the reasons why this infection is so neglected and the consequence of this for the estimated global prevalence. The paper finally points to the gaps in our knowledge and future research needs related to this infection. As Strongyloides infections have the potential to develop into severe disease in certain population subgroups, untreated infections could cause serious problems in the community. Therefore, we need to carefully investigate this parasite in order to develop and implement effective control programmes. en
dc.language English en
dc.subject Neglected diseases en
dc.subject Helminthic diseases en
dc.subject Strongyloidiasis en
dc.subject Strongyloides stercoralis en
dc.subject Disease burden en
dc.subject Morbidity en
dc.subject Diagnosis en
dc.subject Treatment en
dc.subject Control strategies en
dc.subject Research needs en
dc.subject Developing countries en
dc.title Strongyloidiasis; the most neglected of the neglected tropical diseases? en
dc.type Article en
dc.citation.issue 10 en
dc.citation.jtitle Transactions of the Royal Society of Tropical Medicine and Hygiene en
dc.citation.volume 103 en
dc.citation.pages 967-972 en
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/19328508
dc.citation.jabbreviation Trans R Soc Trop Med Hyg en


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