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Associating community prevalence of Schistosoma mansoni infection with prevalence of signs and symptoms

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Show simple item record Van der Werf, M. J. en_US de Vlas, S. J. en_US Looman, C. W. N. en_US Nagelkerke, N. J. D. en_US Habbema, J. D. F. en_US Engels, D. en_US 2007-12-06T14:34:26Z 2007-12-06T14:34:26Z 2002 en_US
dc.identifier.issn 0001-706X en_US
dc.identifier.other ITG-P2B en_US
dc.identifier.other PARAS en_US
dc.identifier.other U-SCHISTO en_US
dc.identifier.other JIF en_US
dc.identifier.other DOI en_US
dc.identifier.other ABSTRACT en_US
dc.description.abstract Information on the prevalence of morbidity is needed for re-calculation of the Global Burden of Disease (WHO) due to Schistosoma mansoni. This study presents a statistical association which can be used to predict the prevalence of morbidity from the prevalence of S. mansoni in a community. We collected data from field studies reporting prevalence of infection and prevalence of morbidity. Data on infection prevalence were standardised to a default diagnostic sensitivity (i.e. Kato-Katz technique 41.7 mg). The data were described by an expression related to logistic regression. We determined associations between prevalence of infection and prevalence of early morbidity (diarrhoea, blood in stool and abdominal pain), hepatosplenic morbidity and late morbidity (haematemesis and ascitis). Diarrhoea and blood in stool due to S. mansoni infection mainly occurs in communities with a high prevalence of infection. An influence on hepatosplenic morbidity is already present at low community prevalence of infection. For the aspecific symptom abdominal pain we did not find an association. en_US
dc.language English en_US
dc.subject Helminthic diseases en_US
dc.subject Schistosomiasis en_US
dc.subject Schistosoma mansoni en_US
dc.subject Morbidity rate en_US
dc.subject Measurement en_US
dc.subject Signs and symptoms en_US
dc.subject Clinical manifestations en_US
dc.subject Diarrhea en_US
dc.subject Blood in stool en_US
dc.subject Abdominal pain en_US
dc.subject Hepatomegaly en_US
dc.subject Splenomegaly en_US
dc.subject Hematemesis en_US
dc.subject Ascites en_US
dc.title Associating community prevalence of Schistosoma mansoni infection with prevalence of signs and symptoms en_US
dc.type Article en_US
dc.citation.issue 2 en_US
dc.citation.jtitle Acta Tropica en_US
dc.citation.volume 82 en_US
dc.citation.pages 127-137 en_US
dc.citation.jabbreviation Acta Trop en_US

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