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Comparison of the Kato-Katz technique, hatching test and indirect hemagglutination assay (IHA) for the diagnosis of Schistosoma japonicum infection in China

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dc.contributor.author Yu, J. M. en_US
dc.contributor.author de Vlas, S. J. en_US
dc.contributor.author Jiang, Q. W. en_US
dc.contributor.author Gryseels, B. en_US
dc.date.accessioned 2007-12-06T14:34:36Z
dc.date.available 2007-12-06T14:34:36Z
dc.date.issued 2007 en_US
dc.identifier.issn 1383-5769 en_US
dc.identifier.doi http://dx.doi.org/10.1016/j.parint.2006.11.002
dc.identifier.other ITG-PLA en_US
dc.identifier.other PARAS en_US
dc.identifier.other U-SCHISTO en_US
dc.identifier.other DIREC en_US
dc.identifier.other JIF en_US
dc.identifier.other DOI en_US
dc.identifier.other ABSTRACT en_US
dc.identifier.uri http://hdl.handle.net/10390/360
dc.description.abstract The Kato-Katz technique (duplicate 41.7 mg fecal smears), hatching test and indirect hemagglutination assay (IHA) were compared for their ability to detect human Schistosoma japonicum infection in two endemic villages (Zhonjiang and Zhuxi) in rural China. The hatching test (using a nylon bag, and based on about 30 g of feces) and IHA are conventional Chinese diagnostic methods. In both villages, the trends of prevalences with age and sex were comparable for the different methods. In Zhuxi, Kato-Katz examinations of stools from 7 different days and hatching were available, which could be used as a reliable gold standard. This resulted for IHA in a sensitivity of 80% and a specificity of 48%. The sensitivity of the Kato-Katz technique using one stool specimen was 68%, twice that of hatching (33%). In Zhonjiang, however, hatching resulted in more positive cases than Kato-Katz (prevalence 31% vs. 24%). Apparently, the result of the hatching test depends on environmental factors such as temperature and water quality. Although imperfect, Kato-Katz is recommended out of the three evaluated techniques as the method of choice for large-scale screening of S. japonicum. Hatching is much more tedious, provides inconsistent and only qualitative results, and is not much more sensitive than Kato-Katz. Its poor specificity makes IHA unsuitable for individual screening, but it may be more effective for community diagnosis. en_US
dc.language English en_US
dc.subject Helminthic diseases en_US
dc.subject Schistosomiasis en_US
dc.subject Schistosoma japonicum en_US
dc.subject Laboratory diagnosis en_US
dc.subject Kato-Katz technique en_US
dc.subject Indirect hemagglutination test en_US
dc.subject Hatching test en_US
dc.subject Sensitivity en_US
dc.subject Specificity en_US
dc.subject Comparative study en_US
dc.subject China en_US
dc.subject Asia, East en_US
dc.subject Far East en_US
dc.title Comparison of the Kato-Katz technique, hatching test and indirect hemagglutination assay (IHA) for the diagnosis of Schistosoma japonicum infection in China en_US
dc.type Article en_US
dc.citation.issue 1 en_US
dc.citation.jtitle Parasitology International en_US
dc.citation.volume 56 en_US
dc.citation.pages 45-49 en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/17188018
dc.citation.jabbreviation Parasitol Int en_US


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