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Anthelminthic resistance in human helminths: a review

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dc.contributor.author Geerts, S. en_US
dc.contributor.author Gryseels, B. en_US
dc.date.accessioned 2007-12-06T14:36:11Z
dc.date.available 2007-12-06T14:36:11Z
dc.date.issued 2001 en_US
dc.identifier.issn 1360-2276 en_US
dc.identifier.doi http://dx.doi.org/10.1046/j.1365-3156.2001.00774.x
dc.identifier.other ITG-A1A en_US
dc.identifier.other ITG-PLA en_US
dc.identifier.other ANIMAL en_US
dc.identifier.other U-ANIMAL en_US
dc.identifier.other PARAS en_US
dc.identifier.other U-SCHISTO en_US
dc.identifier.other JIF en_US
dc.identifier.other DOI en_US
dc.identifier.other ABSTRACT en_US
dc.identifier.other DIREC en_US
dc.identifier.other MULTI en_US
dc.identifier.other FTB en_US
dc.identifier.uri http://hdl.handle.net/10390/511 en_US
dc.description The definitive version is available at www3.interscience.wiley.com
dc.description.abstract We briefly review reports on drug resistance in human helminths and compare the factors which contribute to the development of anthelmintic resistance in livestock and man, i.e. high treatment frequency, single-drug regimens, targeting and timing of mass treatments and underdosing. Conclusions are drawn from the mistakes in the treatment and control of livestock helminths. The advantages and inconveniences of current methods for the detection of drug resistance in helminths of livestock are discussed and some suggestions are put forward to standardize the tests for the detection of resistance in human helminths. Finally, based on veterinary experience, some recommendations are made to reduce the risks of development of drug resistance in human helminths. The dramatic and rapid spread of resistance to all major classes of veterinary anthelmintics should be a warning against too strong a reliance on drugs in helminth control programmes. en_US
dc.language English en_US
dc.publisher Blackwell Publishing
dc.subject Helminthic diseases en_US
dc.subject Drug resistance en_US
dc.subject Human en_US
dc.subject Animal en_US
dc.subject Causes en_US
dc.subject Detection en_US
dc.subject Tests en_US
dc.subject Standardization en_US
dc.subject Risk reduction en_US
dc.subject Review of the literature en_US
dc.title Anthelminthic resistance in human helminths: a review en_US
dc.type Article en_US
dc.citation.issue 11 en_US
dc.citation.jtitle Tropical Medicine and International Health en_US
dc.citation.volume 6 en_US
dc.citation.pages 915-921 en_US
dc.publisher.place Oxford
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/11703846
dc.citation.jabbreviation Trop Med Int Health en_US


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