Institute of Tropical Medicine Antwerp
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African bovine trypanosomiasis: the problem of drug resistance

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dc.contributor.author Geerts, S. en_US
dc.contributor.author Holmes, P. H. en_US
dc.contributor.author Diall, O. en_US
dc.contributor.author Eisler, M. C. en_US
dc.date.accessioned 2007-12-06T14:36:12Z
dc.date.available 2007-12-06T14:36:12Z
dc.date.issued 2001 en_US
dc.identifier.issn 1471-4922 en_US
dc.identifier.doi http://dx.doi.org/10.1016/S1471-4922(00)01827-4
dc.identifier.other JIF en_US
dc.identifier.other ITG-A1A en_US
dc.identifier.other ANIMAL en_US
dc.identifier.other U-ANIMAL en_US
dc.identifier.other DOI en_US
dc.identifier.other ABSTRACT en_US
dc.identifier.uri http://hdl.handle.net/10390/513
dc.description.abstract The three trypanocides used to control tsetse-transmitted trypanosomiasis in domestic animals in Africa have been in use for over 40 years and, not surprisingly, resistance of trypanosomes to these drugs has emerged. Because of the relatively limited market in Africa and the high costs of developing and licensing new drugs, international pharmaceutical companies have shown little interest in the development of new trypanocides for use in either animals or humans. Therefore, the current challenge is to achieve optimal use of the relatively old existing drugs, and it is in this context that the problem of drug resistance has to be quantified--as discussed here by Stanny Geerts, Peter Holmes, Oumar Diall and Mark Eisler. en_US
dc.language English en_US
dc.publisher Cell Press en_US
dc.subject Protozoal diseases en_US
dc.subject Animal diseases en_US
dc.subject Trypanosomiasis, African en_US
dc.subject Drug resistance en_US
dc.subject Review en_US
dc.title African bovine trypanosomiasis: the problem of drug resistance en_US
dc.type Article en_US
dc.citation.issue 1 en_US
dc.citation.jtitle Trends in Parasitology en_US
dc.citation.volume 17 en_US
dc.citation.pages 25-28 en_US
dc.publisher.place St. Louis en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/11137737
dc.identifier.url http://www.trends.com/pt/default.htm en_US
dc.citation.jabbreviation Trends Parasitol en_US


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