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Detection of antibodies to the Ehrlichia ruminantium MAP1-B antigen in goat sera from three communal land areas of Zimbabwe by an indirect enzyme-linked immunosorbent assay

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dc.contributor.author Kakono, O. en_US
dc.contributor.author Hove, T. en_US
dc.contributor.author Geysen, D. en_US
dc.contributor.author Mahan, S. en_US
dc.date.accessioned 2007-12-06T14:36:19Z
dc.date.available 2007-12-06T14:36:19Z
dc.date.issued 2003 en_US
dc.identifier.issn 0030-2465 en_US
dc.identifier.other ITG-A3A en_US
dc.identifier.other ANIMAL en_US
dc.identifier.other U-ANIMAL en_US
dc.identifier.other JIF en_US
dc.identifier.other ABSTRACT en_US
dc.identifier.uri http://hdl.handle.net/10390/537
dc.description.abstract A total of 1,286 caprine serum samples collected from three communal land areas in Zimbabwe from March 1999 to February 2000 were tested for Ehrlichia ruminantium antibodies using the indirect MAP1-B enzyme-linked immunosorbent assay. Of the 480 samples tested from Mudzi, a non-heartwater area, 425 (89.4 %) were positive. In the heartwater endemic areas, of the 441 samples 352 (79.4 %) from Gwanda and 300 of the 365 samples (83.2 %) from Bikita tested positive. The seroprevalence in the Bikita and Gwanda (approaching 90 %) is consistent with reports in related serological surveys that puts the seroprevalence of E. ruminantium in goats from endemic areas of Zimbabwe at 90 %. However, the high seroprevalence in the non-heartwater area of Mudzi is unexpected and can be a result of the presence of a serologically cross-reacting organism, which has to be isolated and characterized. The results need to be confirmed by alternative tests, based on molecular diagnostic tools. There were no significant differences in seroprevalence between the three sampling areas as there were between the three sampling periods. The highest corresponded with the period January to February (peak tick activity) and the lowest with the period July to September (minimal tick activity). en_US
dc.language English en_US
dc.subject Animal diseases en_US
dc.subject Goats en_US
dc.subject Heartwater en_US
dc.subject Ehrlichia ruminantium en_US
dc.subject Laboratory diagnosis en_US
dc.subject Seroprevalence en_US
dc.subject ELISA en_US
dc.subject Antibodies en_US
dc.subject MAP1-B en_US
dc.subject Specificity en_US
dc.subject Zimbabwe en_US
dc.subject Africa, Southern en_US
dc.title Detection of antibodies to the Ehrlichia ruminantium MAP1-B antigen in goat sera from three communal land areas of Zimbabwe by an indirect enzyme-linked immunosorbent assay en_US
dc.type Article en_US
dc.citation.jtitle Onderstepoort Journal of Veterinary Research en_US
dc.citation.volume 70 en_US
dc.citation.pages 243-249 en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/14621321
dc.citation.jabbreviation Onderstepoort J Vet Res en_US


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