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A seroepidemiological study of human cysticercosis in West Cameroon

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dc.contributor.author Nguekam, J. P. en_US
dc.contributor.author Zoli, A. P. en_US
dc.contributor.author Zogo, P. O. en_US
dc.contributor.author Kamga, A. C. T. en_US
dc.contributor.author Speybroeck, N. en_US
dc.contributor.author Dorny, P. en_US
dc.contributor.author Brandt, J. en_US
dc.contributor.author Losson, B. en_US
dc.contributor.author Geerts, S. en_US
dc.date.accessioned 2007-12-06T14:36:36Z
dc.date.available 2007-12-06T14:36:36Z
dc.date.issued 2003 en_US
dc.identifier.issn 1360-2276 en_US
dc.identifier.doi http://dx.doi.org/10.1046/j.1365-3156.2003.01000.x
dc.identifier.other ITG-A5A en_US
dc.identifier.other ITG-A6A en_US
dc.identifier.other ITG-A7A en_US
dc.identifier.other ITG-ALA en_US
dc.identifier.other ANIMAL en_US
dc.identifier.other U-ANIMAL en_US
dc.identifier.other DOI en_US
dc.identifier.other JIF en_US
dc.identifier.other FTB en_US
dc.identifier.other ABSTRACT en_US
dc.identifier.uri http://hdl.handle.net/10390/588
dc.description The definitive version is available at www3.interscience.wiley.com
dc.description.abstract We studied the occurrence of human cysticercosis in 4993 individuals from three rural communities of Menoua Division, West Province of Cameroon. Circulating antigens of Taenia solium metacestodes were detected in 0.4%, 1.0% and 3.0% of the serum samples taken in Bafou, Bamendou and Fonakekeu, respectively, and examined using a monoclonal antibody-based enzyme-linked immunosorbent assay. This test detects only carriers of living cysticerci and gives thus a good idea of the presence of active cysticercosis. The percentage of persons infected with cysticercosis increased with age. Twenty-two of the 34 seropositives underwent computed tomography (CT) of the brain. Thirteen of them were CT-scan positive, which shows that neurocysticercosis was present in 59.1% of the tested seropositive persons. No living cysticerci were detected among 20 seronegative people. About 20.6% of the seropositives had a history of or current taeniasis against only 1.9% of the seronegatives. Based on these figures and on the data on porcine cysticercosis (prevalence: 11%) and human taeniasis (prevalence: 0.13%) collected in the same region, we conclude that T. solium cysticercosis is an endemic, but overlooked public health problem in West Cameroon. en_US
dc.language English en_US
dc.publisher Blackwell Publishing
dc.subject Helminthic diseases en_US
dc.subject Cysticercosis en_US
dc.subject Taenia solium en_US
dc.subject Incidence en_US
dc.subject Seroepidemiology en_US
dc.subject Ag-ELISA en_US
dc.subject Neurocysticercosis en_US
dc.subject CT-scanning en_US
dc.subject Cameroon en_US
dc.subject Africa, Central en_US
dc.title A seroepidemiological study of human cysticercosis in West Cameroon en_US
dc.type Article en_US
dc.citation.issue 2 en_US
dc.citation.jtitle Tropical Medicine and International Health en_US
dc.citation.volume 8 en_US
dc.citation.pages 144-149 en_US
dc.publisher.place Oxford
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/12581440
dc.citation.jabbreviation Trop Med Int Health en_US


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