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Infection with versus exposure to Taenia solium: what do serological test results tell us?

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Show simple item record Praet, N. Rodriguez-Hidalgo, R. Speybroeck, N. Ahounou, S. Benitez-Ortiz, W. Berkvens, D. Van Hul, A. Barrionuevo-Samaniego, M. Saegerman, C. Dorny, P. 2010-08-18T12:09:21Z 2010-08-18T12:09:21Z 2010
dc.identifier.issn 0002-9637
dc.identifier.other ITG-A1A
dc.identifier.other ITG-A3A
dc.identifier.other ITG-A4B
dc.identifier.other ITG-A6A
dc.identifier.other ITG-A7A
dc.identifier.other ITG-ALA
dc.identifier.other ANIMAL
dc.identifier.other U-ANIMAL
dc.identifier.other JIF
dc.identifier.other DOI
dc.identifier.other Abstract
dc.identifier.other UPD24
dc.description.abstract Taenia solium cysticercosis is an endemic zoonosis in many developing countries. Serological tests are the most appropriate diagnostic tools to understand the transmission dynamics of the parasite, but the performances of these methods in such a setting are not known. A south Ecuadorian human population living in an endemic area was tested using three common serological tests. Because none of them is a gold standard, a Bayesian Latent Class analysis was used to estimate the test characteristics. Two definitions of a case were considered to differentiate between prevalence of current infection and prior exposure to the parasite. Differences between the performances of the same test in function of the definition of a case were observed. This study shows that test results and prior information should be interpreted carefully in a Bayesian analysis framework, particularly when the latter is based on clinical studies en
dc.language English en
dc.subject Helminthic diseases en
dc.subject Zoonoses en
dc.subject Cysticercosis en
dc.subject Taenia solium en
dc.subject Diagnostics en
dc.subject Rapid diagnostic tests en
dc.subject Serological en
dc.subject Test kits en
dc.subject Performance en
dc.subject Comparison en
dc.subject Infection en
dc.subject Latent class analysis en
dc.subject Ag-ELISA en
dc.subject EITB en
dc.subject Ab-ELISA en
dc.subject Sensitivity en
dc.subject Specificity en
dc.subject Ecuador en
dc.subject America, Latin en
dc.title Infection with versus exposure to Taenia solium: what do serological test results tell us? en
dc.type Article en
dc.citation.issue 2 en
dc.citation.jtitle American Journal of Tropical Medicine and Hygiene en
dc.citation.volume 83 en
dc.citation.pages 413-415 en
dc.citation.jabbreviation Am J Trop Med Hyg en

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