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Control of viral replication after cessation of HAART

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dc.contributor.author Van Gulck, E.
dc.contributor.author Heyndrickx, L.
dc.contributor.author Bracke, L.
dc.contributor.author Coppens, S.
dc.contributor.author Florence, E.
dc.contributor.author Buvé, A.
dc.contributor.author Lewi, P.
dc.contributor.author Vanham, G.
dc.date.accessioned 2011-02-22T14:28:18Z
dc.date.available 2011-02-22T14:28:18Z
dc.date.issued 2011
dc.identifier.issn 1742-6405
dc.identifier.doi http://dx.doi.org/10.1186/1742-6405-8-6
dc.identifier.other ITG-M1B
dc.identifier.other ITG-M2B
dc.identifier.other ITG-M3B
dc.identifier.other ITG-M4B
dc.identifier.other ITG-C5A
dc.identifier.other ITG-M6A
dc.identifier.other ITG-MLA
dc.identifier.other MULTI
dc.identifier.other MICRO
dc.identifier.other U-VIROL
dc.identifier.other U-HIVSTD
dc.identifier.other CLINIC
dc.identifier.other U-HIVCLI
dc.identifier.other DOI
dc.identifier.other URL
dc.identifier.other Electronic
dc.identifier.other Abstract
dc.identifier.other UPD31
dc.identifier.other FTA
dc.identifier.uri http://hdl.handle.net/10390/6476
dc.description.abstract We describe two patients who did not experience a viral rebound after cessation of HAART which was initiated for progressive disease. CD4 T-cell count remained stable in one patient and progressively declined in the other, despite apparent viral control. We failed to identify any immune activation or genetic markers that could offer an explanation for this unusual "secondary controller" status. But their viruses are clearly less fit compared to viruses from rebounders. en
dc.language English en
dc.subject Viral diseases en
dc.subject HIV en
dc.subject AIDS en
dc.subject HAART en
dc.subject Antiretrovirals en
dc.subject Treatment outcome en
dc.subject Viral load en
dc.subject Replication en
dc.subject Case reports en
dc.subject CD4 lymphocyte count en
dc.subject Viral fitness en
dc.subject Belgium en
dc.subject Europe, West en
dc.title Control of viral replication after cessation of HAART en
dc.type Article-E en
dc.citation.issue 6 en
dc.citation.jtitle AIDS Research and Therapy en
dc.citation.volume 8 en
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/21314914
dc.identifier.url http://www.aidsrestherapy.com/content/8/1/6
dc.citation.jabbreviation AIDS Res Ther en


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