Institute of Tropical Medicine Antwerp
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The use of Interferon-gamma release assays for tuberculosis screening in international travelers

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dc.contributor.author Apers, L.
dc.contributor.author Yansouni, C.
dc.contributor.author Soentjens, P.
dc.contributor.author Vekemans, M.
dc.contributor.author Bottieau, E.
dc.date.accessioned 2011-06-01T09:45:40Z
dc.date.available 2011-06-01T09:45:40Z
dc.date.issued 2011
dc.identifier.issn 1523-3847
dc.identifier.doi http://dx.doi.org/10.1007/s11908-011-0173-0
dc.identifier.other ITG-C1A
dc.identifier.other ITG-C2B
dc.identifier.other ITG-C4A
dc.identifier.other ITG-CLA
dc.identifier.other CLINIC
dc.identifier.other U-HIVCLI
dc.identifier.other U-TROPIC
dc.identifier.other DOI
dc.identifier.other Abstract
dc.identifier.other UPD34
dc.identifier.uri http://hdl.handle.net/10390/6579
dc.description.abstract Tuberculosis (TB) infection is relatively frequent among travellers to high incidence-countries, especially in long-term travellers and those involved in health work. It is important to diagnose recent infection, both for the affected individual and to prevent further transmission. Based on published literature, we assess the value of interferon-gamma release assays (IGRAs) as a complement to or replacement of the tuberculin skin test (TST) for the diagnosis of latent TB infection in the setting of a travel clinic. A comparison of available IGRAs with the TST in terms of operating characteristics and practical considerations is presented. We conclude that IGRAs offer some practical advantages that may benefit certain well-defined patient groups of a travel clinic, but that current evidence is incomplete. We identify research questions to better define the role of IGRAs in these populations. en
dc.language English en
dc.subject Bacterial diseases en
dc.subject Tuberculosis en
dc.subject Mycobacterium tuberculosis en
dc.subject Screening en
dc.subject Diagnosis en
dc.subject Travelers en
dc.subject Risk groups en
dc.subject Evaluation en
dc.subject Interferon-gamma en
dc.subject Assays en
dc.subject Tuberculin test en
dc.title The use of Interferon-gamma release assays for tuberculosis screening in international travelers en
dc.type Article en
dc.citation.issue 3 en
dc.citation.jtitle Current Infectious Disease Reports en
dc.citation.volume 13 en
dc.citation.pages 229-235 en
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/21312007
dc.citation.jabbreviation Curr Infect Dis Rep en


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