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Natural Leishmania donovani/Leishmania aethiopica hybrids identified from Ethiopia

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dc.contributor.author Odiwuor, S.
dc.contributor.author De Doncker, S.
dc.contributor.author Maes, I.
dc.contributor.author Dujardin, J. C.
dc.contributor.author Van der Auwera, G.
dc.date.accessioned 2011-12-15T12:45:54Z
dc.date.available 2011-12-15T12:45:54Z
dc.date.issued 2011
dc.identifier.issn 1567-1348
dc.identifier.doi http://dx.doi.org/10.1016/j.meegid.2011.04.026
dc.identifier.other ITG-P1B
dc.identifier.other ITG-P2B
dc.identifier.other ITG-P3B
dc.identifier.other ITG-P4A
dc.identifier.other ITG-PLA
dc.identifier.other PARAS
dc.identifier.other U-PROTO
dc.identifier.other JIF
dc.identifier.other DOI
dc.identifier.other Abstract
dc.identifier.other UPD41
dc.identifier.uri http://hdl.handle.net/10390/6766
dc.description.abstract Natural hybridization events have been demonstrated between closely and distantly related Leishmania groups despite a predominantly clonal and endogamically sexual mode of reproduction. Here we report the first natural hybrid between Leishmania aethiopica and Leishmania donovani, as evidenced from the analysis of several clones from strain MHOM/ET/94/ABAUY. Targeted species-identification PCRs revealed the presence of both genotypes, and amplified fragment length polymorphisms indicated that the clones are genetically in an intermediate position between both parental species, being more closely related to L. aethiopica. The possible scenario facilitating hybrid formation is not clear, but is discussed in relation to epidemiological data. en
dc.language English en
dc.subject Protozoal diseases en
dc.subject Visceral en
dc.subject Leishmaniasis en
dc.subject Kala azar en
dc.subject Leishmania donovani en
dc.subject Leishmania aethiopica en
dc.subject Vectors en
dc.subject Sandflies en
dc.subject Hybrids en
dc.subject Identification en
dc.subject Clones en
dc.subject Genotypes en
dc.subject Ethiopia en
dc.subject Africa, East en
dc.title Natural Leishmania donovani/Leishmania aethiopica hybrids identified from Ethiopia en
dc.type Article en
dc.citation.issue 8 en
dc.citation.jtitle Infection, Genetics and Evolution en
dc.citation.volume 11 en
dc.citation.pages 2113-2118 en
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/21558020
dc.citation.jabbreviation Infect Genet Evol en


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