Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

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Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

Graf, F. E.; Ludin, P.; Wenzler, T.; Kaiser, M.; Brun, R.; Pyana, P. P.; Büscher, P.; de Koning, H. P.; Horn, D.; Mäser, P.

Journal Name:

PLoS Neglected Tropical Diseases

Issue Date:

2013

Volume:

Issue:

Pages:

e2475

DOI:

http://dx.doi.org/10.1371/journal.pntd.0002475

Pubmed ID:

http://www.ncbi.nlm.nih.gov/pubmed/24130910

Language:

English

Type:

Article-E

Keywords:

Protozoal diseases
Sleeping sickness
Trypanosomiasis, African
Trypanosoma brucei gambiense
Trypanosoma brucei rhodesiense
Vectors
Tsetse flies
Glossina morsitans
Drug susceptibility
Drug resistance
Pentamidine
Melarsoprol
Sensitivity
Phenotyping
Genotyping
Strains
Isolation
Mutations
In vitro
Cultivation
Africa, General

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