Institute of Tropical Medicine Antwerp
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Species typing in dermal leishmaniasis

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dc.contributor.author Van der Auwera, G.
dc.contributor.author Dujardin, J. C.
dc.date.accessioned 2015-08-19T09:28:20Z
dc.date.available 2015-08-19T09:28:20Z
dc.date.issued 2015
dc.identifier.issn 0893-8512
dc.identifier.doi http://dx.doi.org/10.1128/CMR.00104-14
dc.identifier.other ITG-B1A
dc.identifier.other ITG-BLA
dc.identifier.other DBM
dc.identifier.other U-MOLPAR
dc.identifier.other JIF
dc.identifier.other DOI
dc.identifier.other Abstract
dc.identifier.other UPD58
dc.identifier.uri http://hdl.handle.net/10390/8413
dc.description.abstract SUMMARY: Leishmania is an infectious protozoan parasite related to African and American trypanosomes. All Leishmania species that are pathogenic to humans can cause dermal disease. When one is confronted with cutaneous leishmaniasis, identification of the causative species is relevant in both clinical and epidemiological studies, case management, and control. This review gives an overview of the currently existing and most used assays for species discrimination, with a critical appraisal of the limitations of each technique. The consensus taxonomy for the genus is outlined, including debatable species designations. Finally, a numerical literature analysis is presented that describes which methods are most used in various countries and regions in the world, and for which purposes. en_US
dc.language English en_US
dc.subject Protozoal diseases en_US
dc.subject Cutaneous en_US
dc.subject Leishmaniasis en_US
dc.subject Leishmania donovani en_US
dc.subject Leishmania tropica en_US
dc.subject Leishmania mexicana en_US
dc.subject Leishmania braziliensis en_US
dc.subject Leishmania guyanensis en_US
dc.subject Vectors en_US
dc.subject Sandflies en_US
dc.subject Phlebotomus argentipes en_US
dc.subject Taxonomy en_US
dc.subject Species en_US
dc.subject Polymerase chain reaction en_US
dc.subject PCR en_US
dc.subject rDNA en_US
dc.subject kDNA en_US
dc.subject Antigen detection en_US
dc.subject Assays en_US
dc.subject Multi-locus sequencing en_US
dc.subject Hybrids en_US
dc.subject Review of the literature en_US
dc.subject Laboratory techniques and procedures en_US
dc.title Species typing in dermal leishmaniasis en_US
dc.type Article en_US
dc.citation.issue 2 en_US
dc.citation.jtitle Clinical Microbiology Reviews en_US
dc.citation.volume 28 en_US
dc.citation.pages 264-294 en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/25672782
dc.citation.jabbreviation Clin Microbiol Rev en_US


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