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Paternal transmission of a secondary symbiont during mating in the viviparous tsetse fly

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dc.contributor.author De Vooght, L.
dc.contributor.author Caljon, G.
dc.contributor.author Van Hees, J.
dc.contributor.author Van Den Abbeele, J.
dc.date.accessioned 2015-08-27T11:38:33Z
dc.date.available 2015-08-27T11:38:33Z
dc.date.issued 2015
dc.identifier.issn 0737-4038
dc.identifier.doi http://dx.doi.org/10.1093/molbev/msv077
dc.identifier.other ITG-B1B
dc.identifier.other ITG-B2A
dc.identifier.other ITG-B3B
dc.identifier.other ITG-BLA
dc.identifier.other DBM
dc.identifier.other U-VPROT
dc.identifier.other JIF
dc.identifier.other DOI
dc.identifier.other FTA
dc.identifier.other OAA
dc.identifier.other Abstract
dc.identifier.other UPD59
dc.identifier.uri http://hdl.handle.net/10390/8463
dc.description.abstract Sodalis glossinidius, a maternally-inherited secondary symbiont of the tsetse fly, is a bacterium in the early/intermediate state of the transition towards symbiosis, representing an important model for investigating establishment and evolution of insect-bacteria symbiosis. The absence of phylogenetic congruence in tsetse-Sodalis co-evolution and the existence of Sodalis genotypic diversity in field flies is suggestive for a horizontal transmission route. However, to date no natural mechanism for the horizontal transfer of this symbiont has been identified. Using novel methodologies for the stable fluorescent-labeling and introduction of modified Sodalis in tsetse flies we unambiguously show that male-borne Sodalis is i) horizontally transferred to females during mating and ii) subsequently vertically transmitted to the progeny i.e. paternal transmission. This mixed mode of transmission has major consequences regarding Sodalis' genome evolution since it can lead to co-infections creating opportunities for lateral gene transfer which in turn could affect the interaction with the tsetse host. en_US
dc.language English en_US
dc.subject Protozoal diseases en_US
dc.subject Sleeping sickness en_US
dc.subject Trypanosomiasis, African en_US
dc.subject Trypanosoma brucei gambiense en_US
dc.subject Trypanosoma brucei rhodesiense en_US
dc.subject Vectors en_US
dc.subject Tsetse flies en_US
dc.subject Glossina morsitans morsitans en_US
dc.subject Sodalis glossinidius en_US
dc.subject Symbionts en_US
dc.subject Mating en_US
dc.subject Disease transmission, vertical en_US
dc.subject Genetic diversity en_US
dc.title Paternal transmission of a secondary symbiont during mating in the viviparous tsetse fly en_US
dc.type Article en_US
dc.type Letter en_US
dc.citation.issue 8 en_US
dc.citation.jtitle Molecular Biology and Evolution en_US
dc.citation.volume 32 en_US
dc.citation.pages 1977-1980 en_US
dc.identifier.pmid http://www.ncbi.nlm.nih.gov/pubmed/25851957
dc.citation.jabbreviation Mol Biol Evol en_US


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