Institute of Tropical Medicine Antwerp
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Predictors of mortality among tuberculosis-HIV-coinfected persons in Southwest Ethiopia: a case-control study

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Show simple item record Deribe, K. Yami, A. Deribew, A. Mesfin, N. Colebunders, R. Van geertruyden, J. P. Woldie, M. Maja, T. 2015-08-27T12:31:56Z 2015-08-27T12:31:56Z 2015
dc.identifier.issn 2325-9574
dc.identifier.other ITG-C5A
dc.identifier.other DCS
dc.identifier.other U-HIVCLI
dc.identifier.other DOI
dc.identifier.other Abstract
dc.identifier.other UPD59
dc.identifier.other NOBIT
dc.description.abstract Background:Tuberculosis (TB) remains the most common cause of death in people living with HIV/AIDS. The aim of the present study was to identify predictors of mortality in TB-HIV-coinfected patients. Methods:We conducted an unmatched case-control study among a cohort of TB-HIV-coinfected adults who were on antiretroviral therapy (ART). Cases comprised 69 TB-HIV-coinfected patients who died during this period. For each case, we selected 3 (207) TB-HIV-coinfected patients who were alive during the end of the follow-up period. Results:Male sex (odds ratio [OR] = 2.04, 95% confidence interval [CI]: 1.04-4.02), being bedridden at enrollment (OR = 2.84, 95% CI: 1.17-6.89), and cough of more than 2 weeks during initiation of ART (OR = 4.75 95% CI: 2.14-10.56) were the best predictors of mortality among TB-HIV-infected patients. Conclusion:Mortality among TB-HIV-coinfected patients accounted for a considerable number of deaths among the cohort. Patients with cough at ART initiation and with poor functional status should be strictly followed to reduce death. en_US
dc.language English en_US
dc.subject Viral diseases en_US
dc.subject HIV en_US
dc.subject AIDS en_US
dc.subject Co-infections en_US
dc.subject Bacterial diseases en_US
dc.subject Tuberculosis en_US
dc.subject Mycobacterium tuberculosis en_US
dc.subject Epidemiology en_US
dc.subject Mortality en_US
dc.subject Predictors en_US
dc.subject Gender en_US
dc.subject Cough en_US
dc.subject Causes of death en_US
dc.subject Follow-up en_US
dc.subject Ethiopia en_US
dc.subject Africa, East en_US
dc.title Predictors of mortality among tuberculosis-HIV-coinfected persons in Southwest Ethiopia: a case-control study en_US
dc.type Article en_US
dc.citation.issue 3 en_US
dc.citation.jtitle Journal of the International Association of Providers of AIDS Care en_US
dc.citation.volume 14 en_US
dc.citation.pages 269-273 en_US
dc.citation.jabbreviation J Int Assoc Provid AIDS Care en_US

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