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Human African trypanosomiasis [seminar]

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Show simple item record Büscher, P. Cecchi, G. Jamonneau, V. Priotto, G. 2017-07-24T08:15:43Z 2017-07-24T08:15:43Z 2017
dc.identifier.issn 0140-6736
dc.description.abstract Human African trypanosomiasis (sleeping sickness) is a parasitic infection that almost invariably progresses to death unless treated. Human African trypanosomiasis caused devastating epidemics during the 20th century. Thanks to sustained and coordinated efforts over the past 15 years, the number of reported cases has fallen to an historically low level. Fewer than 3000 cases were reported in 2015, and the disease is targeted for elimination by WHO. Despite these recent successes, the disease is still endemic in parts of sub-Saharan Africa, where it is a considerable burden on rural communities, most notably in central Africa. Since patients are also reported from non-endemic countries, human African trypanosomiasis should be considered in differential diagnosis for travellers, tourists, migrants, and expatriates who have visited or lived in endemic areas. In the absence of a vaccine, disease control relies on case detection and treatment, and vector control. Available drugs are suboptimal, but ongoing clinical trials provide hope for safer and simpler treatments. en_US
dc.language English en_US
dc.subject Trypanosomiasis-African en_US
dc.subject Sleeping sickness en_US
dc.subject Protozoal diseases en_US
dc.subject Trypanosoma brucei gambiense en_US
dc.subject Trypanosoma brucei rhodesiense en_US
dc.subject Protozoology en_US
dc.subject Epidemiology en_US
dc.subject Diagnosis en_US
dc.subject Treatment en_US
dc.subject Control en_US
dc.subject Africa-Central en_US
dc.subject Congo-Kinshasa en_US
dc.subject Review of the literature en_US
dc.title Human African trypanosomiasis [seminar] en_US
dc.type Article en_US
dc.citation.jtitle Lancet en_US
dc.citation.volume 390 en_US
dc.citation.pages 1-13 en_US
dc.citation.jabbreviation Lancet en_US

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