Institute of Tropical Medicine Antwerp
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A 54-year-old Philippine sailor with fever and jaundice

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dc.contributor.author Van Dijck, C. en_US
dc.contributor.author Van Esbroeck, M. en_US
dc.contributor.author Rutsaert, R. en_US
dc.date.accessioned 2017-12-18T12:56:09Z
dc.date.available 2017-12-18T12:56:09Z
dc.date.issued 2016 en_US
dc.identifier.issn 1784-3286 en_US
dc.identifier.doi http://dx.doi.org/10.1080/17843286.2015.1105606 en_US
dc.identifier.other http://lib.itg.be/pdf/itg/2016/2016acbe0319.pdf en_US
dc.identifier.other ITG-C2A; DCS; U-CLCB; JIF; DOI; PDF; PMC; Abstract; DSPACE64 en_US
dc.identifier.uri http://hdl.handle.net/10390/9916
dc.description.abstract A 54-year-old man presented with fever, vomiting, jaundice and conjunctival injection. These clinical signs, together with the presence of mild inflammation, hepatitis and severe acute kidney injury, lead to the suspicion of leptospirosis. Infection was serologically confirmed and treatment with ceftriaxone and intermittent haemodialysis was followed by rapid clinical and biochemical recovery. Worldwide, leptospirosis is an emerging pathogen as a result of overpopulation and flooding, but due to increasing tourism also in other regions. In Belgium, clinicians must be aware of endemic as well as imported cases of leptospirosis and differentiate them from hantavirus infections. Leptospirosis is a zoonosis that is transmitted through the urine of chronically colonized animals, mainly rats. Infection can be asymptomatic, present as a mild inflammatory syndrome or cause a severe icterohaemorrhagic disease with multiple organ failure and a high mortality rate. Initial serological diagnosis requires confirmation with a microscopic agglutination assay in a reference laboratory. Treatment is mainly supportive. Antibiotics are often used although mild acute infection often is self-limiting and there is uncertainty about the influence of antibiotic therapy on the duration of fever or mortality. In general, patients fully recover with no remaining organ damage. en_US
dc.language English en_US
dc.relation.uri http://www.ncbi.nlm.nih.gov/pubmed/27075788 en_US
dc.subject Leptospirosis en_US
dc.subject Bacterial diseases en_US
dc.subject Zoonoses en_US
dc.subject Fever en_US
dc.subject Jaundice en_US
dc.subject Sailors en_US
dc.subject Philippines en_US
dc.subject Asia-Southeast en_US
dc.title A 54-year-old Philippine sailor with fever and jaundice en_US
dc.type Article en_US
dc.citation.issue 5 en_US
dc.citation.jtitle Acta Clinica Belgica en_US
dc.citation.volume 71 en_US
dc.citation.pages 319-322 en_US
dc.citation.abbreviation Acta Clin Belg en_US


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